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TRANSDERMAL TESTING USP 5

PADDLE OVER DISK (USP 5)

 

Using the paddle-over-disk method, a transdermal patch is placed either between a glass disc and an inert PTFE mesh (APPFIVE-HR) or directly onto a stainless steel mesh
(APPFIVE-V35, APPFIVE-V56 and APPFIVE-V80, etc.). These are placed on the bottom of the vessel/glass jar, release side up, under the rotating paddle.

Transdermal tests are performed at 32ºC to simulate the temperature of the skin. Other variables such as elevation and sampling requirements are the same as for USP Method 2 (Paddle Method).
QLA's USP 5 products are compatible with all brands of dissolution testers.

 

Important:
The APPFIVE-HR watch glass patch holder is a borosilicate watch glass with a 17 mesh PTFE screen held together by "Kynar clips". Patches up to 90mm in diameter can be tested. It is compatible with all brands of dissolution testers and conforms exactly to the USP specification.

The patch holders APPFIVE-V35, APPFIVE-V56 and APPFIVE-V80 etc. have stainless steel mesh and can hold different patch sizes. Various mesh sizes are available. Mesh sizes not listed may be available on request.

 

You can't find the right product in the following list or do you have any further questions? We will be happy to help you personally. Please use our contact center to write us an email or call us.

 

Part NoDescriptionOEM Ref
 APPFIVE-HR  Transdermal Patch Holder includes watch glass, (1) 17 mesh screen, (4) Kynar Clips  64-190-092  H
 APPFIVE-HRCLIP  Kynar Clip for APPFIVE-HR  65-190-205  H
 APPFIVE-HRSCR  17 mesh screen for APPFIVE-HR  65-190-190  H
 APPFIVE-HRGLA Watch Glass Only for APPFIVE-HR  QLA
 APPFIVE-V30 APP 5 Paddle over Disk Assembly with 30mm opening and (1) 40 mesh screen, 316 SS  QLA
 APPFIVE-V35  Paddle over Disk Assembly, 35mm opening, 40 mesh screen, 316 SS  12-4200  A
 APPFIVE-V56  Paddle over Disk Assembly, 56mm opening, 120 mesh screen, 316 SS  12-4230  A
 APPFIVE-V80  Paddle over Disk Assembly, 80mm opening, (2) 16x16 mesh screens, 316 SS  QLA
 APP5S16-35  16 Mesh Stainless Steel Screen for APPFIVE-V35 (Pack/25)  QLA
 APP5S16-56 16 Mesh SS Replacement Screens for APPFIVE-V56  QLA
 APP5S16-80 16 Mesh SS Replacement Screens for APPFIVE-V80  QLA
 APP5S20-35  20 Mesh Stainless Steel Screen for APPFIVE-V35 (Pack/25)  QLA
 APP5S20-56 20 Mesh Stainless Steel Screen for APPFIVE-V56 (Pack/25) QLA
 APP5S30-35  30 Mesh Stainless Steel Screen for APPFIVE-V35 (Pack/25)  QLA
 APP5S40-30 40 Mesh SS Replacement Screens for APPFIVE-V30  
 APP5S40-35  40 Mesh Stainless Steel Screen for APPFIVE-V35 (Pack/25)  QLA
 APP5S40-56  40 Mesh Stainless Steel Screen for APPFIVE-V56 (Pack/25)  QLA
 APP5S40-80  40 Mesh SS Replacement Screens for APPFIVE-V80  QLA
 APP5S100-35  100 Mesh SS Replacement Screens for APPFIVE-V35  QLA
 APP5S120-35  120 Mesh SS Replacement Screens for APPFIVE-V35  QLA
 APP5S120-56  120 Mesh Stainless Steel Screen for APPFIVE-V56 (Pack/25)  QLA
 APP5S16-80  16 Mesh Stainless Steel Screen for APPFIVE-V80 (Pack/25)  QLA
 TRANDE-SC  Custom Transdermal Screen, 316 SS  QLA

 

OEM Key
A
= AGILENT
H = HANSON