Testing of semisolids with paddle method (USP 2)
Testing so-called semisolids - such as ointments, creams, lotions and gels - is often a difficult and time-consuming task. The so-called "Vertical Diffusion Cell" - also called the "Franz Cell" - is often used for this purpose, but requires complex troublesome temperature and flow through control! The "Immersion-Cell" is an alternative described by the USP, Chapter <1724> for testing semi-isolables. Despite the easy use with the USP-Apparatus 2 (Paddles) it is less well known.
The advantages of the Immersion-Cell are:
- Can be used in any dissolution tester (also from other manufacturers) with a 200mL - Small Volume Paddle Conversion Kit with 200mL Flat Bottom Vessel.
- Easy filling of the Semisolids into the Immersion-Cell. The desired volume is adjustable.
- Easy membrane attachment.
- Easy tempering with the water bath of the dissolution tester.
- Release with the paddle method, no susceptible flow principle.
- Sampling as usual with the paddle method (mechanical or automated).
We are offering you both possible versions - Model A (with adjustable chamber) or Model B. PVDF, Tuffryn Polysulfone and Strat-M membranes are available as membranes.
Further information can be found under Information.
You don´t find the right product in following list or do you have any further questions? We will be happy to help you personally. Please use our contact center to write us an email or call us.
| Part No | Description |
|---|
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0202.0010
|
RIGGTEK Immersion Cell set, Model A, PTFE
incl. spacers with 0,5/2/4 sq cm opening and Alignment Tools
Used with special 200ml Small Volume Conversion Kit
|
|
0402.0202
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Adapter for Immersion Cell Model A, for RIGGTEK Dissilio, incl. cover
possilble to use with (not included)
200ml clear glass flat bottom peak vessel 1299.0062
included:
- adapter rings
- cover with 2 holes for sample pobes
not included / needed:
- 0402.0171 vessel centering ring
- 1202.0078 2x plugs for sample probe holes
not included:
small volume vessels, paddles, etc.
|
|
1299.0062
|
Vessel, 200ml, flat bottom with peak, for RIGGTEK Dissilio, for Immersion Cell Model A, serialized
|
|
0202.0005
|
Immersion Cell , Model B, PTFE
Support Tool (0202.0007 ), Hand Tool (0202.0009 ) and Installation Rod (0202.0008) available seperately
|
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0202.0006
|
Immersion Cell , Model B, PTFE set of 6
Support Tool (0202.0007 ), Hand Tool (0202.0009 ) and Installation Rod (0202.0008) available seperately
|
|
0402.0203
|
Adapter for Immersion Cell Model B, for RIGGTEK Dissilio, incl. cover
possilble to use with (not included)
200ml clear glass flat bottom vessel 1299.0072
included:
- adapter rings
- cover with 2 holes for sample pobes
not included / needed:
- 0402.0171 vessel centering ring
- 1202.0078 2x plugs for sample probe holes
not included:
small volume vessels, paddles, etc.
|
|
1299.0072
|
Vessel, 200ml, flat bottom, for RIGGTEK Dissilio, for Immersion Cell Model B, serialized
|
| 0202.0007 |
Immersion Cell Support Tool, Model B |
| 0202.0008 |
Immersion Cell Installation Rod Assembly Tool, Model B |
| 0202.0009 |
Immersion Cell Hand Tool Assembly, Model B |
|
1201.0075
|
Small Volume Shaft Adapter, for RIGGTEK Dissilio, Adpater Small Volume Stirring Element to Shaft, SS
|
|
1201.0082
|
Small Volume Mini Paddle, for RIGGTEK Dissilio, also compliant for Immersion Cell, 316SS, serialized, not included / needed:- 1202.0075 Small Volume Shaft Adapter
|
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1202.0079
|
Small Volume Mini Paddle, for RIGGTEK Dissilio, PTFE coated over 316SS, serialized, not included / needed:- 1202.0075 Small Volume Shaft Adapter
|
